Monday, November 24, 2014

How Marijuana Cures Incurable Leukemia

Brave Mykala is Cancer Free

Pediatric cannabis therapy is saving children. Are you surprised? But, that is the modern reality.

Brave Mykala had T-cell acute lymphoblastic leukaemia, a rare, aggressive, and overall deadly form of childhood leukemia. It accounts for 15-18% of childhood leukemia cases. Her DNA has been altered in some way, and it caused her bone marrow to start producing leukemia white blood cells. She fell unwell May 2012, and July 2012 doctors discovered a basketball sized mass of lymphoblasts in her chest. The mass was so large that she was not able to be sedated for risk of death from the pressure on her esophagus and heart.

After all approved treatments failed to stop spreading the disease, she got permission to start the experimental Cannabis Oil treatment July 26th, 2012. By August 2nd, 2012, Lymphoblast percentage in her blood smear dropped from maximum 33% to ZERO.

From this date, Mykayla was in remission. You may here the expert opinion, that cannabis is inappropriate for children. Well, it is hard to disagree. However, cancer is inappropriate for children even to the higher degree.

The anti-tumor effects of cannabinoids and THC have been demonstrated for quite some time now.  In the 1980’s, cannabinoid receptors were discovered in the human brain, which made it obvious that our body has to synthesize something that binds to these receptors. Our bodies produce these compounds in our own endocannabinoid system, which is now known to be responsible for a number of biological functions.  This is why the plant has such a wide therapeutic potential for multiple diseases, including cancer.

Numerous studies have demonstrated again and again the anti-tumoral effects of cannabis. Studies have shown that cannabis completely kills cancer cells, and it has a great impact on rebuilding the immune system. Cannabis has the potential to replace a multitude of pharmaceutical drugs, and it remains a mystery as to why human trials are not under way.

In the United States, there are only two approved treatments for cancer, radiation and chemotherapy.  Scientists have discovered that chemotherapy fuels cancer growth and kills the patient more quickly, yet nothing has been changed.  Both are extremely toxic to the human body. Thanks to a growing awareness related to cannabis medical use, and its high rate of success with individuals choosing to try it as a cancer treatment, more people are starting to realize the healing power of this plant. Coupled with all of the success stories, are hundreds of scientific studies that prove cannabis kills cancer, it’s really becoming a no-brainer.

When you are an adult with cancer, you have the choice to use the two recommended options or refuse treatment and select alternative methods. When you are a child, your parents do not have the option to refuse the approved way without facing legal repercussions, which can include loosing custody of the child.

What is Leukemia?

Leukemia is a type of cancer that affects the blood or bone marrow, most often white blood cells. White blood cells are part of the immune system and play a key role in defending the body against infections.
Leukemia does not refer to a single disease, but rather covers a broad spectrum of diseases. Leukemia can be classified as either chronic or acute, depending on the rate of progression, and by the type of white blood cells that are affected. Acute lymphocytic (or lymphoblastic) leukemia is the most common leukemia that occurs in children.

Most forms of leukemia are treated with chemotherapy. However, treatment becomes less effective when leukemia spreads – usually to the central nervous system, skin and gums, and sometimes in the form of tumors.

Furthermore, treatment outcomes vary greatly and, in many instances, leukemia will eventually resurface after a period of remission.

Latest Studies

One of the latest studies in UK confirmed that compounds derived from marijuana can kill cancerous cells in patients with leukemia.

"Cannabinoids have a complex action; it hits a number of important processes that cancers need to survive," explained study author Dr. Wai Liu, an oncologist at St. George's University of London. "For that reason, it has really good potential over other drugs that only have one function. I am impressed by its activity profile, and feel it has a great future, especially if used with standard chemotherapies."

Dr. Wai Liu studied six different non-psychoactive cannabinoids (compounds derived from marijuana that do not get the user high like its THC component does). He found that certain non-psychoactive cannabinoids “resulted in dramatic reductions in cell viability” and “caused a simultaneous arrest at all phases of the cell cycle,” according to the study summary posted online.

In 2012, researchers at the California Pacific Medical Center in San Francisco found that CBD — a non-psychoactive chemical compound found in cannabis — can stop metastasis in some kinds of aggressive cancer.

How THC Kills Cancer Cells

The social and legal restrictions on Marijuana use still affect amount of efforts and funding for the related anti-cancer research.  

Insight into how THC (the main psychoactive component of the cannabis plant) cures Cancer is explained by molecular biologist, Dr. Christina Sanchez, in the video above. A scientist at the Compultense University in Madrid, Spain, she relayed her long-time studies and enlightening findings with Cannabis Planet TV.

If you want to understand the Cannabis components action against cancer in more details, here is the explanation provided by biochemist Dennis Hill in more details.

First let us look at what keeps cancer cells alive, and then we will come back and examine how the cannabinoids CBD (cannabidiol) and THC (tetrahydrocannabinol) unravels cancer’s aliveness.

In every cell, there is a family of interconvertible sphingolipids that specifically manage the life and death of that cell. This profile of factors is called the “Sphingolipid Rheostat.” If endogenous ceramide (a signaling metabolite of sphingosine-1-phosphate) is high, then cell death (apoptosis) is imminent. If ceramide is low, the cell is strong in its vitality.

Very simply, when THC connects to the CB1 or CB2 cannabinoid receptor site on the cancer cell, it causes an increase in ceramide synthesis, which drives cell death. A normal healthy cell does not produce ceramide in the presence of THC, thus is not affected by the cannabinoid.

The cancer cell dies, not because of cytotoxic chemicals, but because of a tiny little shift in the mitochondria. Within most cells there is a cell nucleus, numerous mitochondria (hundreds to thousands), and various other organelles in the cytoplasm. The purpose of the mitochondria is to produce energy (ATP) for cell use. As ceramide starts to accumulate, turning up the Sphingolipid Rheostat, it increases the mitochondrial membrane pore permeability to cytochrome c, a critical protein in energy synthesis. Cytochrome c is pushed out of the mitochondria, killing the source of energy for the cell.

Ceramide also causes genotoxic stress in the cancer cell nucleus generating a protein called p53, whose job it is to disrupt calcium metabolism in the mitochondria. If this were not enough, ceramide disrupts the cellular lysosome, the cell’s digestive system that provides nutrients for all cell functions. Ceramide, and other sphingolipids, actively inhibit pro-survival pathways in the cell leaving no possibility at all of cancer cell survival.

The key to this process is the accumulation of ceramide in the system. This means taking therapeutic amounts of CBD and THC, steadily, over a period of time, keeping metabolic pressure on this cancer cell death pathway.

Gaining Recognition

Though federal law still prohibits the use of Cannabis, as much as 25 States have legalized its use for medical purposes for certain medical conditions.

Official government site Cancer.Gov lists the following positive effects of Cannabis for cancer patients, stating that Cannabinoids may be useful in treating the side effects of cancer and cancer treatment.

The possible effects of cannabinoids include:
* Anti-inflammatory activity.
* Blocking cell growth.
* Preventing the growth of blood vessels that supply tumors.
* Antiviral activity.
* Relieving muscle spasms caused by multiple sclerosis.

”The cannabinoids in cannabis prevent cancer cells from spreading, and they contribute to cancer cell death because they hit some receptors that are generally up-regulated in cancer cells,” confirms Professor Marja Jäättelä, who heads the Cell Death and Metabolism Research Unit at the Danish Cancer Society. “This has been demonstrated in several studies. There is no doubt that cannabinoids are very effective at killing cancer cells.

Sources and Additional Information:

1 comment:

Danielle said...

I was once a thyroid cancer patient. I was diagnosed of thyroid cancer and it almost end my life. I did chemo and radiation many times but the cancer keeps returning and it began to weaken my body and i was unable to move from one place to another. i was living in pain for 3 years, i tried looking for other means of treatment when i came across cannabis oil for cancer treatment. I did so many findings and it was all positive and i was a bit relief knowing that my cancer can be cured permanently. I contacted Leed cancer cancer in England via to purchase the cannabis oil. After using this cannabis oil for treatment as directed, my doctor confirmed that i am free from cancer that it was a miracle. I am writing this because a lot of people are suffering from cancer out there and they need help. Try and get the cannabis oil for treatment and you will live again.